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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4C
All Species:
58.48
Human Site:
Y262
Identified Species:
91.9
UniProt:
P60510
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60510
NP_002711.1
307
35080
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Chimpanzee
Pan troglodytes
XP_001148385
265
30391
C235
A
N
D
I
D
M
I
C
R
A
H
Q
L
V
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_858953
324
36761
Y279
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5BJ92
307
35049
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505222
306
34933
Y261
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Chicken
Gallus gallus
P48463
309
35545
Y265
T
I
F
S
A
P
N
Y
C
Y
R
C
G
N
Q
Frog
Xenopus laevis
Q6IP91
307
35104
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76932
307
35323
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
Y288
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Sea Urchin
Strong. purpuratus
XP_799172
307
35031
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Poplar Tree
Populus trichocarpa
XP_002317353
305
34758
Y260
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Maize
Zea mays
NP_001170721
307
34933
Y262
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48528
305
34707
Y260
T
V
W
S
A
P
N
Y
C
Y
R
C
G
N
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48580
327
37273
Y283
T
I
F
S
A
P
N
Y
C
Y
R
C
G
N
Q
Conservation
Percent
Protein Identity:
100
86.3
N.A.
94.7
N.A.
N.A.
99.6
N.A.
91.2
66
99
98
N.A.
91.5
N.A.
74.7
93.4
Protein Similarity:
100
86.3
N.A.
94.7
N.A.
N.A.
99.6
N.A.
92.5
81.2
99.6
99.6
N.A.
96.4
N.A.
82.5
97
P-Site Identity:
100
0
N.A.
100
N.A.
N.A.
100
N.A.
100
80
100
100
N.A.
100
N.A.
100
100
P-Site Similarity:
100
6.6
N.A.
100
N.A.
N.A.
100
N.A.
100
93.3
100
100
N.A.
100
N.A.
100
100
Percent
Protein Identity:
82
81.4
N.A.
82
N.A.
60.8
Protein Similarity:
89.9
90.8
N.A.
90.5
N.A.
75.8
P-Site Identity:
100
93.3
N.A.
100
N.A.
80
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
94
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
94
0
0
94
0
0
0
% C
% Asp:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
94
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
14
0
7
0
0
7
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
0
94
0
0
0
0
0
0
94
0
% N
% Pro:
0
0
0
0
0
94
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
14
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
94
0
0
0
0
% R
% Ser:
0
0
0
94
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
94
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
80
0
0
0
0
0
0
0
0
0
0
0
7
74
% V
% Trp:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
94
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _